CRRT Mastery Series — Book 2 Extracorporeal Therapies in Critical Care

CRRT Mastery Series — Book 2

Extracorporeal Therapies in Critical Care

A high-stakes 2 a.m. call. A Guillain-Barré patient crashing. A TTP diagnosis that will kill within days if the wrong therapy is chosen. Standard renal replacement therapy won’t answer these moments — but the extracorporeal techniques that do are the ones rarely taught well. This book moves beyond conventional CRRT into the advanced therapies every intensivist, DrNB, and EDIC candidate must master, framed the way the decision actually unfolds at the bedside.

What’s inside

• Therapeutic plasma exchange — timing in Guillain-Barré and TTP, with plasma volume calculations worked step-by-step
• Centrifugal vs membrane plasmapheresis — the trade-offs that decide which you reach for
• Hemadsorption & hemoperfusion — cytokine adsorption in septic shock and where it earns its place
• ECMO–CRRT integration — combined circuits managed as one system, not two
• Drug dosing across extracorporeal support — adjusting antibiotics and sedatives on concurrent circuits
• Real bedside cases, not protocol lists — each chapter follows the clinical decision as it happens
• Examiner-framed teaching — mechanism and rationale, so you learn the reasoning, not a memorised protocol

Educational reference only — always follow your unit’s local protocols and manufacturer guidance.

By Dr. Gunadhar Padhi — Chief Intensivist, MD, IDCCM, FCCCM, ECMO (Paris); author of the EDIC preparation series.